Cell Respiration (IB Topic C1.2)

Essential Idea(s): Cell respiration supplies energy for the functions of life. Anaerobic respiration is respiration without oxygen; aerobic respiration is respiration with it.

Unit Length: 3 Lessons (+4 AHL)

  Guiding Questions

◊ What are the roles of hydrogen and oxygen in the release of energy in cells?

◊ How is energy distributed and used inside cells?

IB Statement(s) and Objective(s)

C1.2.1: ATP as the molecule that distributes energy within cells

C1.2.2: Life processes within cells that ATP supplies with energy

C1.2.3: Energy transfers during interconversions between ATP and ADP

  • Describe the structure of ATP
  • State three example uses of ATP for life processes
  • State three reasons why cellular respiration must be continuously performed by all cells
  • Outline energy transfer in the formation and use of ATP

 

C1.2.4: Cell respiration as a system for producing ATP within the cell using energy released from carbon compounds

  • Define “cell respiration”
  • List common substrates of cellular respiration
  • Define gas exchange and cell respiration

 

C1.2.5: Differences between anaerobic and aerobic cell respiration in humans

  • State the types of organic compounds used in cellular respiration by animals and plants
  • Define “anaerobic respiration”
  • State the word equation for aerobic cellular respiration
  • State the word equation for anaerobic cellular respiration
  • State the location of anaerobic respiration
  • State the location of aerobic respiration
  • Compare anaerobic respiration in yeasts and humans

 

C1.2.6: Variables affecting the rate of cell respiration

  • Outline variables affecting the rate of cell respiration in an organism
  • Outline the use of a respirometer to measure cellular respiration rate

Additional Higher Level Topics

B2.2.4: Adaptations of the mitochondrion for production of ATP by aerobic cell respiration

  • Explain the advantage of a double membrane in mitochondria

C1.2.7: Role of NAD as a carrier of hydrogen and oxidation by removal of hydrogen during cell respiration

  • Outline oxidation and reduction reactions (redox reactions) – (in terms of movement of electrons, hydrogen or oxygen atoms)
  • Define ‘electron carrier’
  • State the name of the electron carrier molecules used in cellular respiration

 

C1.2.8: Conversion of glucose to pyruvate by stepwise reactions in glycolysis with a net yield of ATP and reduced NAD

  • State the formula for the glycolysis reaction
  • Summarize the purpose of glycolysis 
  • Outline the glycolysis reaction, including phosphorylation, lysis and energy harvest

 

C1.2.9: Conversion of pyruvate to lactate as a means of regenerating NAD in anaerobic cell respiration

  • State the reason why NAD must be regenerated in anaerobic respiration

 

C1.2.10: Anaerobic cell respiration in yeast and its use in brewing and baking

  • Compare anaerobic respiration in yeasts and humans
  • Outline how anaerobic respiration in yeast is used in baking
  • Outline how anaerobic respiration in yeast is used in ethanol production

 

C1.2.11: Oxidation and decarboxylation of pyruvate as a link reaction in aerobic cell respiration

  • Define decarboxylation and oxidation
  • Summarize the reactant and products of the link reaction
  • State the primary substrates used in the link reaction

 

C1.2.12: Oxidation and decarboxylation of acetyl groups in the Krebs cycle with a yield of ATP and reduced NAD

  • State the location of the Krebs Cycle (aka Citric Acid Cycle)
  • Outline the events of the Krebs cycle (include: citrate (6C) and oxaloacetate (4C), as well as the formation of additional electron carriers (FADH and NADH)
  • State the names of the electron carriers formed during the Krebs cycle

 

C1.2.13: Transfer of energy by reduced NAD to the electron transport chain in the mitochondrion

  • State that NADH and FADH2 carry electrons to the electron transport chain on the mitochondrial inner membrane

 

C1.2.14: Generation of a proton gradient by flow of electrons along the electron transport chain

C1.2.15: Chemiosmosis and the synthesis of ATP in the mitochondrion

C1.2.16: Role of oxygen as terminal electron acceptor in aerobic cell respiration

  • State that at the electron transport chain, FADH2 and NADH given electrons to electron carrier proteins
  • Define oxidative phosphorylation
  • Define chemiosmosis
  • State that oxygen is the final electron acceptor in aerobic cellular respiration
  • State the number of ATP and water molecules generated by oxidative phosphorylation
  • Explain how oxidative phosphorylation produces ATP

 

C.1.2.17: Differences between lipids and carbohydrates as respiratory substrates

  • Outline the energy storage of lipids compared to carbohydrates
  • Compare the use of carbohydrates and lipids as respiratory substrates in aerobic and anaerobic respiration
  • Outline the process by which lipids can be a substrate for respiration
Activities: = podcast / = inquiry 5 / = Write it Ӕ = The academy  / = Read it

Ⓛ (analysis): Writing a Conclusion and Analysis The “Back-end” of a Lab Report 

Assignment details here

Following any experiment, you should have enough data to:

  • Make a graph 
  • Use the graph to write a conclusion
  • Write an analysis of the experiment 

For this assignment, you will be writing a shortened version of these parts. Make sure you understand how a respirometer works, then have at it! 

If you get stuck, here are guides to help you:

Once finished, watch this walkthrough video to see how you did

 

📄 (recommended): Flipchart to Respire (👭 max 4)

This is a memorization-heavy unit that is all about chemical cycles and processes. Grab a big piece of flipchart paper and make a diagram to summarize all the steps of cellular respiration. Here are the requirements: 

  • Start by placing “Cellular Respiration” at the far left of your map. 
  • Create separate bubbles/boxes for major processes such as glycolysis, the link reaction, the Krebs cycle, etc. 
  • Include additional bubbles for critical molecules (e.g., glucose, pyruvate, ATP, NADH, FADH2, CO2, O2, water) and structures (e.g., mitochondrion, cytoplasm) 
  • Draw lines between the bubbles to illustrate connections, and along each line, write short, descriptive words or verbs that explain the relationship (e.g., “yields,” “is converted into,” “produces,” “transfers electrons to”) 
  • Your map should clearly show the flow of energy and matter, the role of electron carriers, and the distinction between aerobic and anaerobic pathways. 

Be creative and use arrows, colors, or symbols to enhance clarity and emphasize important steps. 

 

: The Big Squeeze (💁/ 👭 max 2)

Want to know what lactic acid in your muscles feels like? Grab a tennis ball and get squeezing. This lab will help you learn the basics of anaerobic respiration, and will get you some lab skills practice (which helps prep you for the upcoming IA). More lab practice is always a good idea!

 

: Anaerobic Respiration (💁/ 👭max 2)

There are several factors that can affect how quickly yeast can respire. Choose one of the following labs (verify ahead of time that our school lab has all required equipment). Answer all questions at the end of each lab.

 

/: Why Foodies Love Biology (💁/ 👭max 2)

Bread. Beer. Wine (and all other alcohol). Kimchi. Cheese. Soy Sauce. Fish sauce. Yogurt. Kombucha. Yes…a world without anaerobic respiration would also be a world without any of these beloved things (plus many others). Together with your fellow podcasters, choose at least one food/drink example. Explain how anaerobic respiration works, (including a complete chemical equation); and then, discuss a world in which these things don’t exist. How would history have been different? How might cultures be different?

 

(recommended): The Fun in Fermentation – A Student Discovers the Science of Wine-Making (💁)

Humans have been fermenting wine for over 6,000 years. Read this story/case study about a student first learning how to make wine – and the key science behind the process. Write out answers to the questions on pages 3-4 (you can ignore the rest). Your answers should be complete sentences with an attempt at quality writing. 

 

/: Beer (💁/ 👭max 3)

Beer is liquid bread. Just about all beer is made from the same key 4 ingredients (water, yeast, grains, and hops). Yet there are thousands of different types of beer in the world. Dive deeper into the science of beer (here’s another good video), and write/discuss the following: 

  1. Explain the reaction that ferments beer
  2. Explain the role of the grain and the yeast
  3. Think and answer: What enzyme (in the body) achieves the same end result as the process of mashing? 
  4. From a scientific standpoint, why was beer historically the ‘purest’ drink one could find…even safer than water?

 

Aerobic Respiration Activities: 

 

: “Inquiry 5”: Q&A on Aerobic Respiration (💁/ 👭max 2)

Create a list of 5 inquiry questions related to aerobic respiration. Remember that good inquiry questions are conceptual / open-ended…

SUCH AS:  “How could mitochondria evolve through 

                    natural selection?” 

         NOT:  “Where does the krebs cycle take place?” 

If working solo, write out answers to your own questions with high quality explanations. If working in pairs, record yourselves asking each other your 5 questions.

 

Ӕ: The Academy – Respiration (💁)

Choose from: 

  • Glycolysis
  • The link reaction
  • The Krebs Cycle
  • The Electron Transport Chain

…and screencast Khan Academy-style video of you teaching a lesson of that phase of aerobic respiration. Include all the key terms and details, making sure you give an overview of where and when that phase takes place within respiration. The final product should be in the 5-10 minute range. Go here for inspiration!

 

Other: Puzzle: The Krebs Cycle (💁/ 👭max 2)

Print out the hexagons in this mini puzzle about the krebs cycle, then cut them out. Arrange them in correct order, then take a snapshot of your work and upload it to G. Classroom.  

 

Role-Play: The Electron Transport Chain (💁/ 👭NO max )

A great whole-class activity — just requires a bit of prep. Assuming you want to pull it off, you can “teach” this activity as a lesson. Organize the entire class into roles (e.g. NADH) and use tennis balls and golf balls to represent H+ ions and electrons. See if the class can figure out how they should be passing each across the “intracellular membrane”.

 

Other (Puzzle/Game): The Electron Transport Game (💁/ 👭max 2)

Print out the game pieces for the Electron Transport Game, and follow the directions as they’re stated. Take a picture of your game board as you’re playing, and submit that to G. Classroom.

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Extras: 

TED Talk: We Need to Feed the World: on the vital role of bread in feeding the world. 

Review worksheet 1

Review  worksheet 2